2,496 research outputs found
Simplifying Satellite and Ground Data Validation with Level-2 Subsetting
We demonstrate that scientists can simplify their satellite data validation workflow with the use of NASA Godddard Earth Sciences Data and Information Services Center (GES DISC) subsetting services. We perform a sample validation of Aura ozone products collocated with ground-based ozone measurements using subsetting services to trim satellite data to only the relevant user-defined variables and spatio-temporal region. Because the subsetting service automatically returns only relevant data granules that adhere to a set of user-defined coincidence criteria, user workload is greatly reduced. Moreover, the resultant data files are substantially smaller than full data granules due to the subsetting service further culling the data to the relevant geospatio-temporal coincidence criteria, user-defined variables, and user-defined dimensions of variables. This decreases data download throughput and file storage requirements. The validation presented here quantifies the time and file size savings that can be achieved by utilizing subsetting services within the satellite data validation workflow
Exponential beams of electromagnetic radiation
We show that in addition to well known Bessel, Hermite-Gauss, and
Laguerre-Gauss beams of electromagnetic radiation, one may also construct
exponential beams. These beams are characterized by a fall-off in the
transverse direction described by an exponential function of rho. Exponential
beams, like Bessel beams, carry definite angular momentum and are periodic
along the direction of propagation, but unlike Bessel beams they have a finite
energy per unit beam length. The analysis of these beams is greatly simplified
by an extensive use of the Riemann-Silberstein vector and the Whittaker
representation of the solutions of the Maxwell equations in terms of just one
complex function. The connection between the Bessel beams and the exponential
beams is made explicit by constructing the exponential beams as wave packets of
Bessel beams.Comment: Dedicated to the memory of Edwin Powe
Explicit MBR All-Symbol Locality Codes
Node failures are inevitable in distributed storage systems (DSS). To enable
efficient repair when faced with such failures, two main techniques are known:
Regenerating codes, i.e., codes that minimize the total repair bandwidth; and
codes with locality, which minimize the number of nodes participating in the
repair process. This paper focuses on regenerating codes with locality, using
pre-coding based on Gabidulin codes, and presents constructions that utilize
minimum bandwidth regenerating (MBR) local codes. The constructions achieve
maximum resilience (i.e., optimal minimum distance) and have maximum capacity
(i.e., maximum rate). Finally, the same pre-coding mechanism can be combined
with a subclass of fractional-repetition codes to enable maximum resilience and
repair-by-transfer simultaneously
Generalized Gravi-Electromagnetism
A self consistant and manifestly covariant theory for the dynamics of four
charges (masses) (namely electric, magnetic, gravitational, Heavisidian) has
been developed in simple, compact and consistent manner. Starting with an
invariant Lagrangian density and its quaternionic representation, we have
obtained the consistent field equation for the dynamics of four charges. It has
been shown that the present reformulation reproduces the dynamics of individual
charges (masses) in the absence of other charge (masses) as well as the
generalized theory of dyons (gravito - dyons) in the absence gravito - dyons
(dyons). key words: dyons, gravito - dyons, quaternion PACS NO: 14.80H
Experience with onabotulinumtoxinA (BOTOX) in chronic refractory migraine: focus on severe attacks
The objective of this study is to analyse our experience in the treatment of refractory chronic migraine (CM) with onabotulinumtoxinA (BTA) and specifically in its effects over disabling attacks. Patients with CM and inadequate response or intolerance to oral preventatives were treated with pericranial injections of 100 U of TBA every 3 months. The dose was increased up to 200 U in case of no response. The patients kept a headache diary. In addition, we specifically asked on the effect of BTA on the frequency of disabling attacks, consumption of triptans and visits to Emergency for the treatment of severe attacks. This series comprises a total of 35 patients (3 males), aged 24–68 years. All except three met IHS criteria for analgesic overuse. The number of sessions with BTA ranged from 2 to 15 (median 4) and nine (26%) responded (reduction of >50% in headache days). However, the frequency of severe attacks was reduced to an average of 46%. Oral triptan consumption (29 patients) was reduced by 50% (from an average of 22 to 11 tablets/month). Those six patients who used subcutaneous sumatriptan reduced its consumption to a mean of 69% (from 4.5 to 1.5 injections per month). Emergency visits went from an average of 3 to 0.4 per trimester (−83%). Six patients complained of mild adverse events, transient local cervical pain being the most common. Although our data must be taken with caution as this is an open trial, in clinical practice treatment of refractory CM with BTA reduces the frequency of disabling attacks, the consumption of triptans and the need of visits to Emergency, which makes this treatment a profitable option both clinically and pharmacoeconomically
Shift-Symmetric Configurations in Two-Dimensional Cellular Automata: Irreversibility, Insolvability, and Enumeration
The search for symmetry as an unusual yet profoundly appealing phenomenon,
and the origin of regular, repeating configuration patterns have long been a
central focus of complexity science and physics. To better grasp and understand
symmetry of configurations in decentralized toroidal architectures, we employ
group-theoretic methods, which allow us to identify and enumerate these inputs,
and argue about irreversible system behaviors with undesired effects on many
computational problems. The concept of so-called configuration shift-symmetry
is applied to two-dimensional cellular automata as an ideal model of
computation. Regardless of the transition function, the results show the
universal insolvability of crucial distributed tasks, such as leader election,
pattern recognition, hashing, and encryption. By using compact enumeration
formulas and bounding the number of shift-symmetric configurations for a given
lattice size, we efficiently calculate the probability of a configuration being
shift-symmetric for a uniform or density-uniform distribution. Further, we
devise an algorithm detecting the presence of shift-symmetry in a
configuration.
Given the resource constraints, the enumeration and probability formulas can
directly help to lower the minimal expected error and provide recommendations
for system's size and initialization. Besides cellular automata, the
shift-symmetry analysis can be used to study the non-linear behavior in various
synchronous rule-based systems that include inference engines, Boolean
networks, neural networks, and systolic arrays.Comment: 22 pages, 9 figures, 2 appendice
Quaternion Analysis for Generalized Electromagnetic Fields of Dyons in Isotropic Medium
Quaternion analysis of time dependent Maxwell's equations in presence of
electric and magnetic charges has been developed and the solutions for the
classical problem of moving charges (electric and magnetic) are obtained in
unique, simple and consistent manner
Ketamine for Refractory Headache: A Retrospective Analysis.
BACKGROUND AND OBJECTIVES: The burden of chronic headache disorders in the United States is substantial. Some patients are treatment refractory. Ketamine, an N-methyl-D-aspartate antagonist, provides potent analgesia in subanesthetic doses in chronic pain, and limited data suggest it may alleviate headache in some patients.
METHODS: We performed a retrospective study of 61 patients admitted over 3 years for 5 days of intravenous therapy that included continuous ketamine to determine responder rate and patient and ketamine infusion characteristics. Pain ratings at 2 follow-up visits were recorded. An immediate responder was a patient with decrease of 2 points or greater in the numerical rating scale (0-10) from start to final pain in the hospital. Sustained response at office visits 1 and 2 was determined based on maintaining the 2-point improvement at those visits. Patients were assessed daily for pain and adverse events (AEs).
RESULTS: Forty-eight (77%) of the 61 patients were immediate responders. There were no differences regarding demographics, opioid use, or fibromyalgia between immediate responders and nonresponders. Maximum improvement occurred 4.56 days (mean) into treatment. Sustained response occurred in 40% of patients at visit 1 (mean, 38.1 days) and 39% of patients at visit 2 (mean, 101.3 days). The mean maximum ketamine rate was 65.2 ± 2.8 mg/h (0.76 mg/kg per hour). Ketamine rates did not differ between groups. Adverse events occurred equally in responders and nonresponders and were mild.
CONCLUSIONS: Ketamine was associated with short-term analgesia in many refractory headache patients with tolerable adverse events. A prospective study is warranted to confirm this and elucidate responder characteristics
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